WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Cluster :

Algorithm  Signals from replicates of total worm lysates from wt and strains containing the ain-2::gfp or the ain-2 promoter::gfp transgene were mean normalized and averaged respectively to generate standard profiles of gene expression in these worm strains. Authors then calculated the ratio of signal of each gene from each IP sample to the standard gene expression profile of the corresponding worm strain. Based on this ratio, a percentile rank of each gene relative to all genes in each IP replicate was calculated. The percentile ranks in the three replicates of each IP were averaged. Student t test was utilized to determine if the average percentile ranks of enrichment of individual genes were significantly higher (p value) than the mean enrichment of all genes in the IP samples. To determine the AIN-1 or AIN-2 associated genes, we used the following criteria: (1) average percentile ranks of enrichment is greater than the mean enrichment of all genes in AIN-1 or AIN-2 IP with p < 0.01; (2) average signal in AIN-1 or AIN-2 IP replicates is greater than the background signal (including 2X standard deviation (SD)) (Background signal and SD were calculated based on signals from empty spots on each microarray); (3) criteria 1 is not be satisfied for the same gene in the corresponding control IP. Description  mRNAs that were significantly enriched in the AIN-1 immunoprecipitation samples, compared to the control total mRNAs in the input extracts (p < 0.01).
Primary Identifier  WBPaper00031252:AIN-1_IP_enriched

0 Anatomy Terms

2888 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000001 aap-1 Y110A7A.10 Caenorhabditis elegans
WBGene00000003 aat-2 F07C3.7 Caenorhabditis elegans
WBGene00000004 aat-3 F52H2.2 Caenorhabditis elegans
WBGene00000007 aat-6 T11F9.4 Caenorhabditis elegans
WBGene00000036 ace-2 Y44E3A.2 Caenorhabditis elegans
WBGene00000047 acr-8 ZC504.2 Caenorhabditis elegans
WBGene00000053 acr-14 T05C12.2 Caenorhabditis elegans
WBGene00000055 acr-16 F25G6.3 Caenorhabditis elegans
WBGene00000068 acy-1 F17C8.1 Caenorhabditis elegans
WBGene00000070 acy-3 C44F1.5 Caenorhabditis elegans
WBGene00000072 add-1 F39C12.2 Caenorhabditis elegans
WBGene00000073 add-2 F57F5.4 Caenorhabditis elegans
WBGene00000083 adt-2 F08C6.1 Caenorhabditis elegans
WBGene00000085 aex-2 T14B1.2 Caenorhabditis elegans
WBGene00000090 age-1 B0334.8 Caenorhabditis elegans
WBGene00000092 ags-3 F32A6.4 Caenorhabditis elegans
WBGene00000096 ahr-1 C41G7.5 Caenorhabditis elegans
WBGene00000099 air-2 B0207.4 Caenorhabditis elegans
WBGene00000100 ajm-1 C25A11.4 Caenorhabditis elegans
WBGene00000101 aka-1 D1022.7 Caenorhabditis elegans
WBGene00000106 alg-2 T07D3.7 Caenorhabditis elegans
WBGene00000138 amx-2 B0019.1 Caenorhabditis elegans
WBGene00000140 anc-1 ZK973.6 Caenorhabditis elegans
WBGene00000146 ape-1 F46F3.4 Caenorhabditis elegans
WBGene00000170 aqp-2 C01G6.1 Caenorhabditis elegans
WBGene00000220 atf-2 K08F8.2 Caenorhabditis elegans
WBGene00000222 atf-6 F45E6.2 Caenorhabditis elegans
WBGene00000231 atx-2 D2045.1 Caenorhabditis elegans
WBGene00000232 avr-14 B0207.12 Caenorhabditis elegans
WBGene00000237 bam-2 Y71F9AR.1 Caenorhabditis elegans

0 Life Stages

0 Processes

1 Regulated By Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00015547 ain-1 C06G1.4 Caenorhabditis elegans

0 Regulated By Molecule