WormMine: RNAi WBRNAi00107848

• WormBase ID: WBRNAi00107848
• Genotype: gld-1(q485)
• Phenotype Remark: "(tumor cell) Invasion of the vulva region often results in the appearance of a tumor prolapse that protrudes from the vulva (Fig S2C; Movies S2 and S3). Prolapses form by a flow of individual tumor cells and animals with tumor prolapses are motile and often shed their prolapse. In line with modulation of autophagy affecting tumor growth, inhibition of autophagy leads to an increase in the percentage of animals displaying a tumor prolapse both in gld-1 RNAi and mutant animals (Fig S2D and E)."
• Remark: (Figure S2E) atg-7 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010882	atg-7	M7.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:M7.5	M7.5	1944	IV: 11078818-11079018

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002397	tumor prolapse frequency increased	Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00049105

0 Strain