WormMine: RNAi WBRNAi00087494

• WormBase ID: WBRNAi00087494
• Phenotype Remark: mps-1 RNAi induced defects in body touch sensation, chemotaxis to biotin and lysine, osmotic avoidance, and nose-touch collision. mps-1 RNAi did not affect chemotaxis to benzaldehyde and isoamyl alcohol that are mediated by AWC neurons where mps-1 appears to be expressed, and it did not affect other sensory functions such as chemotaxis to diacetyl, octanol avoidance, and thermotaxis that are mediated by neurons that not appear to express mps-1.
• Remark: Template was genomic DNA.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003403	mps-1	C29F5.4	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C29F5.4	C29F5.4	774	II: 6292652-6292850

1 Laboratories

Primary Identifier
FDX

5 Phenotype

Identifier	Name	Description
WBPhenotype:0000249	osmotic avoidance defective	Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals.
WBPhenotype:0001221	nose touch defective	Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal.
WBPhenotype:0000398	light body touch resistant	Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls.
WBPhenotype:0001565	lysine chemotaxis defective	Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant.
WBPhenotype:0002016	biotin chemotaxis defective	Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant.

5 Phenotype _ Not _ Observed

Identifier	Name	Description
WBPhenotype:0000412	octanol chemotaxis defective	Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant.
WBPhenotype:0000303	diacetyl chemotaxis defective	Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive.
WBPhenotype:0000304	isoamyl alcohol chemotaxis defective	Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive.
WBPhenotype:0000478	isothermal tracking behavior variant	Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature.
WBPhenotype:0000302	benzaldehyde chemotaxis defective	Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive.

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005801

0 Strain