WormMine: RNAi WBRNAi00093059

• WormBase ID: WBRNAi00093059
• Phenotype Remark: RNAi of pat-3 resulted in a dramatic reduction in invadopodia formation with dramatically reduced F-actin structure formation in the anchor cell.
• Remark: Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. To avoid embryonic lethality of pat-3 RNAi, synchronized L1-arrested larvae were grown for 5 h on regular OP50 bacteria in the absence of RNAi. These worms were then transferred to bacteria expressing pat-3 double-stranded RNA.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003930	pat-3	ZK1058.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1058.2	ZK1058.2	2430	III: 3909329-3909400

1 Laboratories

Primary Identifier
NK

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001652	anchor cell invasion variant	Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00043893

0 Strain