WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00070036 Phenotype Remark  13 percent had underdeveloped gonads including animals with no oocyte development and malformed or missing spermathecae. In some animals, at least one arm was fully functional, with the anterior gonad arm consistently more underdeveloped than the posterior arm.
Remark  exact sequence used for RNAi not stated by authors, genomic sequence of gene used for curation

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001967 hlh-28 F31A3.2 Caenorhabditis elegans
WBGene00001968 hlh-29 F31A3.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F31A3.2 F31A3.2 720   X: 17551057-17551226
CDS:F31A3.4 F31A3.4 720   X: 17547817-17548141

0 Laboratories

8 Phenotype

Identifier Name Description
WBPhenotype:0000697 protruding vulva Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
WBPhenotype:0000691 gonad development variant Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
WBPhenotype:0001355 gonad morphology variant Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WBPhenotype:0000006 egg laying defective Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control.
WBPhenotype:0000695 vulva morphology variant Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control.
WBPhenotype:0000038 exploded through vulva The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WBPhenotype:0000696 everted vulva The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
WBPhenotype:0001424 oocyte physiology variant Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00029063

1 Strain

WormBase ID
WBStrain00000001