WormMine: RNAi WBRNAi00079038

• WormBase ID: WBRNAi00079038
• Phenotype Remark: E cell daughters fail to migrate to the interior of the embryo during gastrulation
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of med-1 gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003180	med-1	T24D3.1	Caenorhabditis elegans
WBGene00003181	med-2	K04C2.6	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K04C2.6	K04C2.6	525	III: 6884503-6885027
CDS:T24D3.1	T24D3.1	525	X: 12430609-12431133

1 Laboratories

Primary Identifier
JR

8 Phenotype

Identifier	Name	Description
WBPhenotype:0001276	ectopic expression transgene	Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals.
WBPhenotype:0000354	cell differentiation variant	Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
WBPhenotype:0000779	late embryonic arrest	Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation.
WBPhenotype:0001495	cell division precocious	Cells divide at an earlier stage of development compared to control animals.
WBPhenotype:0001376	transgene expression undetectable cell specific	The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells.
WBPhenotype:0001637	no Intestine	Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
WBPhenotype:0000393	cell migration failure	Characteristic movement of cells from one site to another is abolished compared to control.
WBPhenotype:0001648	no posterior pharynx	Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00004636

0 Strain