WormMine: RNAi WBRNAi00097137

• WormBase ID: WBRNAi00097137
• Phenotype Remark: Animals treated at later larval stages (L2 and L3), thus with reduced exposure to crn-1(RNAi), had many surviving progeny (data not shown). These viable, crn-1(RNAi)-treated embryos accumulated TUNEL-positive nuclei throughout embryonic development, indicating an increase in apoptosis.
• Remark: (Figure 1B) crn-1 RNAi. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000794	crn-1	Y47G6A.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y47G6A.8	Y47G6A.8	1149	I: 3482030-3482119

1 Laboratories

Primary Identifier
CU

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000183	apoptosis increased	Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005978

1 Strain

WormBase ID
WBStrain00000001