WormMine: RNAi WBRNAi00116334

• WormBase ID: WBRNAi00116334
• Phenotype Remark: Centriole duplication does not occur in sas-5(RNAi) embryos, leading to monopolar spindle assembly in each blastomere at the second cell cycle. As a result, a four-cell configuration is never observed.
• Remark: Exact sequence used for RNAi not stated by authors, genomic sequence of gene used for curation. Authors state their RNAi targets nucleotides 301 through 1170 of the genomic sequence.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00009385	sas-5	F35B12.5	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F35B12.5c	F35B12.5c	867	V: 11611222-11611402
CDS:F35B12.5a	F35B12.5a	1215	V: 11610779-11610830

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001876	centriole biogenesis variant	Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00046872

0 Strain