WormMine: RNAi WBRNAi00097884

• WormBase ID: WBRNAi00097884
• Genotype: eri-1(mg366)
• Phenotype Remark: Loss of motor coordination first appeared at the L4 larval stage as a kink in the normal sinusoidal wave that drives locomotion. Movement then gradually declined in adults, often culminating in paralysis. Quantification of movement loss with a swimming assay verified the developmental progression of the Unc phenotype.
• Remark: (Figure 1, text) coq-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000761	coq-1	C24A11.9	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C24A11.9	C24A11.9	1182	I: 5413127-5413207

1 Laboratories

Primary Identifier
NC

4 Phenotype

Identifier	Name	Description
WBPhenotype:0000002	kinker	The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals.
WBPhenotype:0000473	progressive paralysis	Animals become increasingly sluggish/immobilized as they age.
WBPhenotype:0000273	thrashing reduced	The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms.
WBPhenotype:0004017	locomotor coordination variant	Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00036704

0 Strain