WormMine: RNAi WBRNAi00008136

• WormBase ID: WBRNAi00008136
• Phenotype Remark: Observed in >=10% of progeny.
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_7D6

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010015	atad-3	F54B3.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F54B3.3	F54B3.3	1788	II: 10248991-10249365

1 Laboratories

Primary Identifier
KK

14 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000031	slow growth	Any variation that causes a reduction in growth rate compared to control.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001106	spindle orientation variant AB or P1 early emb	The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001177	embryo osmotic pressure sensitive early emb	Embryos rupture when placed on a 2% agar pad and covered with a coverslip.
WBPhenotype:0001139	nuclear envelope assembly variant early emb	Nuclear envelope does not reassemble properly.
WBPhenotype:0001105	P0 spindle position abnormal	Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
WBPhenotype:0000040	one cell arrest early emb	Embryos fail to divide and arrest as one-cell embryos.
WBPhenotype:0001119	cell cycle slow early emb	Embryos take longer to divide during the first and second cell divisions.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0000689	maternal sterile	Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
WBPhenotype:0001123	synchronous second division early emb	AB and P1 divide synchronously.
WBPhenotype:0001153	pronuclear migration failure early emb	Neither of the pronuclei migrate and they never meet.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001