WormMine: RNAi WBRNAi00094571

• WormBase ID: WBRNAi00094571
• Phenotype Remark: bec-1 RNAi results in a more rapid and significant accumulation of Salmonella typhimurium bacteria in the intestinal lumen and inside the intestinal cells, compared to vector controls. bec-1 RNAi animals exhibited fewer autophagosomes and autolysosomes containing the Salmonella typhimurium bacteria and an increase in the number of Salmonella containing vacuoles (SCVs), as determined by electron microscopy.
• Remark: (Figure 1A, 1E-J, Table S1) bec-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000247	bec-1	T19E7.3	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T19E7.3a	T19E7.3a	1128	IV: 5661340-5661525
CDS:T19E7.3b	T19E7.3b	357	IV: 5661340-5661525

1 Laboratories

Primary Identifier
KLJ

3 Phenotype

Identifier	Name	Description
WBPhenotype:0001271	pathogen induced death increased	Animals are more prone to lethality as a result of infection compared to control.
WBPhenotype:0000736	autophagy variant	Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control.
WBPhenotype:0002159	increased pathogen accumulation	Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00035076

1 Strain

WormBase ID
WBStrain00000001