WormMine: RNAi WBRNAi00114534

• WormBase ID: WBRNAi00114534
• Genotype: daf-28(sa191); zcIs4 [phsp-4::GFP]
• Phenotype Remark: Quote from paper: "To determine whether the developmental induction of hsp-4 is dependent on BLMP-1 function, we down-regulated blmp-1 in sa191;phsp-4::GFP animals by RNAi. Under normal growth conditions, sa191 animals that do initiate the dauer program enter the L2d stage by 41 hours postgastrula. We found no effect of blmp-1 RNAi on this initial phsp-4::GFP reporter induction at 41 hours postgastrula in all animals that had L2d morphology (Fig 3A, top row). However, by 42 hours, blmp-1 RNAi caused increased reporter fluorescence in seam cells of these animals, and by 46-47 hours, approximately half of blmp-1 RNAi animals (n= 81) exhibited induction of the reporter in the lateral hypodermis (Fig 3A and 3B)."
• Remark: blmp-1 (WBGene00003847) RNAi.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003847	blmp-1	F25D7.3	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F25D7.3b	F25D7.3b	2406	I: 10409359-10409536
CDS:F25D7.3a	F25D7.3a	2454	I: 10409359-10409536

0 Laboratories

3 Phenotype

Identifier	Name	Description
WBPhenotype:0001236	transgene expression increased	Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001719	unfolded protein response variant	Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0001485	ER stress response variant	Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00056441

0 Strain