WormMine: RNAi WBRNAi00117212

• WormBase ID: WBRNAi00117212
• Phenotype Remark: In all cases where embryos are observed with two partially decondensed pronuclei (equivalent to postmeiotic stage in a wild-type zygote) one pronucleus always had an abnormally high DNA content. These abnormal pronuclei were unequivocally identified as being of oocyte origin following careful examination of embryos that were retained in the uterus and could be oriented. Based upon the high DNA content in oocyte pronuclei and the lack of detectable polar body, we conclude that meiosis fails to occur in air-2(RNAi) embryos.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. Authors did note they used clone yk274b8.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000099	air-2	B0207.4	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:B0207.4	B0207.4	918	I: 5937484-5937551

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000775	meiosis variant	Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes.
WBPhenotype:0001041	meiosis defective early emb	Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00004268

0 Strain