WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00077667 Genotype  rrf-3(pk1426)
Phenotype Remark  Low levels of embryonic lethality prior to the initiation of epidermal morphogenesis, because of gastrulation failure. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00013683 zoo-1 Y105E8A.26 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y105E8A.26a Y105E8A.26a 3492   I: 14529532-14529627
CDS:Y105E8A.26b Y105E8A.26b 3375   I: 14529532-14529627
CDS:Y105E8A.26c Y105E8A.26c 3396   I: 14531977-14532030
CDS:Y105E8A.26d Y105E8A.26d 3120   I: 14536999-14537001

1 Laboratories

Primary Identifier
SU

6 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000062 lethal Animals die prematurely at any stage of the life cycle.
WBPhenotype:0000047 gastrulation variant Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
WBPhenotype:0001478 body elongation variant Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
WBPhenotype:0001136 embryonic morphology variant Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control.
WBPhenotype:0001812 embryonic rupture During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled.

3 Phenotype _ Not _ Observed

Identifier Name Description
WBPhenotype:0001566 ventral enclosure variant Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control.
WBPhenotype:0000926 body wall muscle morphology variant Any variation in the morphological appearance of the body wall muscle compared to control animals.
WBPhenotype:0001292 body wall muscle physiology variant Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00032115

0 Strain