WormMine: RNAi WBRNAi00022772

• WormBase ID: WBRNAi00022772
• Remark: During interphase, cytoplasmic MTs were not affected, but assembly of centrosomal asters failed. Centrosomal asters formed as embryos entered mitosis, but spindle assembly never occurred. Centrosomal ZYG-9 was reduced in tbg-1(RNAi) embryos to 30% of wild-type levels. Both the number of astral microtubules and the kinetics of centrosomal microtubule nucleation were compromised in tbg-1(RNAi) embryos.
• Secondary Identifier: [cgc5320]:tbg-1

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006540	tbg-1	F58A4.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F58A4.8	F58A4.8	1335	III: 9626677-9626991

1 Laboratories

Primary Identifier
TH

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005320

1 Strain

WormBase ID
WBStrain00000001