WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00110188 Genotype  rrf-1(pk1417)
Phenotype Remark  Hermaphrodites accumulate degraded oocytes in the proximal gonad and (or) differentiated oocytes in the distal gonad. Authors found that egrh-1(RNAi) was less effective in rrf-1(pk1417) than in a wild-type background. "Indeed rrf-1(pk1417); egrh-1(RNAi) animals exhibited only a slightincrease in the frequency of oocyte defects when compared with untreated rrf-1(pk1417) mutants. Thus, we conclude that egrh-1 functions in the soma." rrf-1(pk1417) mutants are specifically resistant to RNAi in the soma but remain sensitive to RNAi in the germline. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00007772 egrh-1 C27C12.2 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C27C12.2 C27C12.2 1386   X: 14845944-14846084

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0000186 oogenesis variant Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
WBPhenotype:0001668 oocyte accumulation An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00037082

0 Strain