WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00095097 Phenotype Remark  Hypodermis-specific RNAi of bli-3 caused increased susceptibility to infection and higher relative mortality.
Remark  Hypodermis-specific RNAi of bli-3. In strain NR222 rde-1 is under the expression of a hypodermis-specific promoter in the rde-1(ne219) mutant background. An rde-1 mutation renders the RNAi machinery inactive and the worm is not susceptible to RNAi. However, when this gene is expressed under the control of a tissue-specific promoter, RNAi can then occur in these specific tissues.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000253 bli-3 F56C11.1 Caenorhabditis elegans
WBGene00018771 duox-2 F53G12.3 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F56C11.1 F56C11.1 4494   I: 146623-146748
CDS:F53G12.3 F53G12.3 4512   I: 137845-137886

1 Laboratories

Primary Identifier
GF

2 Phenotype

Identifier Name Description
WBPhenotype:0001013 pathogen susceptibility increased Animals are more prone to infection compared to control.
WBPhenotype:0001271 pathogen induced death increased Animals are more prone to lethality as a result of infection compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00035115

1 Strain

WormBase ID
WBStrain00029103