WormMine: RNAi WBRNAi00114338

• WormBase ID: WBRNAi00114338
• Genotype: Q40::YFP
• Phenotype Remark: RNAi knock-down of arc-1, the C.elegans MID1 homolog, leads to a reduction of inclusion bodies and improved motility similar to the effect of the antidiabetic drugMetformin.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. Authors also don't state how RNAi was delivered.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000180	arc-1	ZK1320.6	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1320.6	ZK1320.6	1620	II: 9674981-9675369

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001405	protein aggregation variant	Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.
WBPhenotype:0001936	resistant to protein aggregation induced paralysis	Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00055135

0 Strain