WormMine: RNAi WBRNAi00069868

• WormBase ID: WBRNAi00069868
• Remark: Authors used a strain expressing a GPF-based reporter harboring a premature termination codon for their experiments. In wild type, mRNAs from this transgene are degraded by the nonsense-mediated mRNA decay (NMD) pathway, and there is no GFP expression. Animals that lack the ability to carry out the NMD pathway will express GFP.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000121	aly-2	F23B2.6	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F23B2.6	F23B2.6	684	IV: 9147475-9147700

0 Laboratories

0 Phenotype

1 Phenotype _ Not _ Observed

Identifier	Name	Description
WBPhenotype:0001538	mRNA surveillance defective	Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00029295

0 Strain