WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00222506 Gene Name  Bma-skpo-2
Sequence Name  ? Bm2245 Organism  Brugia malayi
Automated Description  Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in response to oxidative stress. Is an ortholog of C. elegans skpo-2. Biotype  SO:0001217
Genetic Position  :±
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm2245.1 Bm2245.1   [unknown]
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm2245 Bm2245   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  

0 Downstream Intergenic Region

9 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_F120
  Transcripts that showed significantly lower expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Downregulated
  Transcripts that showed significantly higher expression in L3 larva comparing to in adult. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L3_vs_Adult_Upregulated
  Transcripts that showed significantly higher expression in L4 larva comparing to in adult. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Adult_Upregulated
  Transcripts that showed significantly decreased expression after 5 days of 1uM ivermectin exposure. Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method). WBPaper00049974:ivermectin_1uM_5-day_downregulated
  Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M30_vs_F30
  Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F120_vs_F30
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P9
  Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F30_vs_L4

0 Expression Patterns

3 GO Annotation

Annotation Extension Qualifier
  enables
  involved_in
  enables

0 Homologues

0 Locations

3 Ontology Annotations

Annotation Extension Qualifier
  enables
  involved_in
  enables

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term