WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00224373 Gene Name  Bm4112
Sequence Name  ? Bm4112 Organism  Brugia malayi
Automated Description  Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Biotype  SO:0001217
Genetic Position 
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm4112b.1 Bm4112b.1   [unknown]
Transcript:Bm4112a.1 Bm4112a.1   [unknown]
 

Other

2 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm4112b Bm4112b   [unknown]
CDS:Bm4112a Bm4112a   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  

0 Downstream Intergenic Region

10 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F120_vs_F30
  Transcripts that showed significantly higher expression in L4 larva comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Micro_Upregulated
  Proteins that are enriched in productive tract of adult female Brugia malayi. Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction. WBPaper00048706:productive-tract_enriched
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_M30
  Proteins secreted by B.malayi at L3 larva stage, according to LC-MS-MS. N.A. WBPaper00050454:Secretome_protein
  Transcripts that showed significantly increased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M42_vs_M30
  Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F120_vs_F42
  Transcripts that showed significantly higher expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Upregulated
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P5
  Transcripts that showed significantly increased expression at infective lava stage 3 (iL3) (from mosquitoes), comparing to L3 Day 6 worms. Differential gene expression analysis was performed using both DESeq and EdgeR, and the overlapping genes with FDR<0.01 were retained. WBPaper00059852:B.malayi_iL3_stage_upregulated_vs_L3Day6

0 Expression Patterns

3 GO Annotation

Annotation Extension Qualifier
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  enables
  enables

0 Homologues

0 Locations

3 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term