WormMine: Gene WBGene00225478

• WormBase Gene ID: WBGene00225478
• Gene Name: Bm5217
• Sequence Name: Bm5217
• Organism: Brugia malayi
• Automated Description: Predicted to enable ATP binding activity; DNA binding activity; and DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Predicted to be involved in DNA topological change. Is an ortholog of O. volvulus OVOC8298.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm5217a.1	Bm5217a.1		[unknown]
Transcript:Bm5217b.1	Bm5217b.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm5217b	Bm5217b		[unknown]
CDS:Bm5217a	Bm5217a		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

2 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly higher expression in adult comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:Adult_vs_Micro_Upregulated
	Transcripts that showed significantly decreased expression after 48 hours of 300nM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_300nM_48h_downregulated

0 Expression Patterns

5 GO Annotation

0 Homologues

0 Locations

5 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term