WormMine: Gene WBGene00226151

• WormBase Gene ID: WBGene00226151
• Gene Name: Bm5890
• Sequence Name: Bm5890
• Organism: Brugia malayi
• Automated Description: Predicted to enable extracellular ligand-gated monoatomic ion channel activity and transmembrane signaling receptor activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans unc-49. In C. elegans, unc-49 is involved in gamma-aminobutyric acid signaling pathway; locomotory behavior; and regulation of backward locomotion.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

3 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm5890b.1	Bm5890b.1		[unknown]
Transcript:Bm5890c.1	Bm5890c.1		[unknown]
Transcript:Bm5890a.1	Bm5890a.1		[unknown]

Other

3 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm5890c	Bm5890c		[unknown]
CDS:Bm5890a	Bm5890a		[unknown]
CDS:Bm5890b	Bm5890b		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

7 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly lower expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Downregulated
	Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Micro_Downregulated
	Transcripts that showed significantly higher expression in adult comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:Adult_vs_Micro_Upregulated
	Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M30_vs_L4
	Transcripts that showed significantly lower expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Downregulated
	Transcripts that showed significantly increased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F30_vs_L4
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P11

0 Expression Patterns

6 GO Annotation

0 Homologues

0 Locations

6 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term