WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00044022 Gene Name  AC3.9
Sequence Name  ? AC3.9 Organism  Caenorhabditis elegans
Automated Description  Is affected by several genes including etr-1; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Biotype  SO:0000336
Genetic Position  Length (nt)  ? 2034
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00044022

Genomics

0 Transcripts

 

Other

0 CDSs

0 RNAi Result

36 Allele

Public Name
gk963301
gk963495
gk963496
gk964351
gk962860
gk964304
WBVar01864749
WBVar01864750
WBVar01974617
gk314805
gk911344
gk921852
gk857607
gk467829
gk918598
WBVar01590094
gk502944
WBVar01590093
gk245289
WBVar01631060
WBVar00001435
gk245290
gk245287
gk245288
gk245286
gk245291
gk245292
WBVar01743030
gk918597
gk391465

1 Chromosome

WormBase ID Organism Length (nt)
V Caenorhabditis elegans 20924180  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00044022 10374851 10376884 1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrV_10376885..10376984   100 V: 10376885-10376984 Caenorhabditis elegans

20 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type. DESeq2, fold change > 2, FDR < 0.05. WBPaper00066485:ogt-1(ok1474)_upregulated_neuron
  Transcripts that showed significantly increased expression after animals were treated with 100uM Psora and 250uM Allantoin from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Psora-Allantoin_upregulated
  Transcripts that showed significantly increased expression after animals were treated with 100uM Rapamycin and 50mM Metformin from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rapamycin-Metformin_upregulated
  Transcripts that showed significantly decreased expression in daf-16(mgDf50) comparing to in N2 at L1 larva stage. DESeq v1.20.0 was used to analyze differential gene expression. Transcripts with adjusted p-value < 0.05 were considered differentialled expressed. WBPaper00048971:daf-16(mgDf50)_downregulated_L1
  Transcripts that showed significantly increased expression in daf-2(e1370) comparing to in N2. Student's t-test, fold change > 2, p-value < 0.05. WBPaper00055386:daf-2(e1370)_upregulated
  Germline-enriched and sex-biased expression profile cluster A. hierarchical clustering [cgc6390]:Cluster_A
heat shock: 33C 30min Transcripts that showed significantly decreased expression in hsf-1(RNAi) animals, after heat shock at 33 C for 30min, comparing to in hsf-1(RNAi) animals without heat shock. Transcripts that were differentially expressed in different conditions, compared to the hsf-1(+);-HS control, were determined with CuffDiff, which uses the Benjamini-Hochberg correction for multiple testing to obtain the q-value (the FDR-adjusted the p-value). WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
  Transcripts that showed significantly decreased expression in hsf-1(RNAi) animals comparing to in control animals, without heat shock. Transcripts that were differentially expressed in different conditions, compared to the hsf-1(+);-HS control, were determined with CuffDiff, which uses the Benjamini-Hochberg correction for multiple testing to obtain the q-value (the FDR-adjusted the p-value). WBPaper00049942:hsf-1(RNAi)_downregulated
  Down-regulated genes (fold change > 1.5) in two CoQ-deficient clk-1 mutant strains (e2519, qm30) compared to wild types N2. Fold-changes of intensities were calculated from the arithmetic mean of gene expression values between experimental and corresponding control group. Fold change >= 1.5 was used as cut-off. WBPaper00045774:clk-1_downregulated
  Transcripts that showed significantly increased expression in alg-1(gk204) comparing to in N2 at 5-days post L4 adult hermaphrodites. DESeq, fold change > 2, adjusted p-value < 0.05. WBPaper00054758:alg-1(gk204)_upregulated
  transcripts that showed significantly decreased expression after N2 animals were exposed to 20 uM bortezomib for 4 hours. Differential expression analyses were performed using limma-voom in Galaxy. Fold change > 2, FDR < 0.05. WBPaper00062345:bortezomib_4h_downregulated_N2
control(maintained under normal lab light (mostly dark, in incubators).) vs UVC-exposed(exposed to 7.5 J/m2 UVC radiation 3 times, 24 h apart (48 h total).) at just prior to the third UVC dose (48h). Genes differentially expressed in control vsafter UVC exposure without EtBr treatment, at the -1h timepoint (just prior to the third UVC dose (48h)). Transcripts were defined as fold-change >1.2, p < 0.05 based on Rosetta Resolver analysis for all pairwise treatment comparisons. The fold-change refers to the second intensity over the first. WBPaper00041939:control_vs_UVC-exposed_48h
Bacteria infection: Burkholderia pseudomallei BpR15 Genes that showed decreased expression in adult animals after 12 hour exposure to B. pseudomallei R15 vs. exposure to OP50 After array normalization, significance analysis of microarray was performed on data from individual time points (two class unpaired response) to identify genes with small but consistent changes. A false-discovery rate (FDR) of ~1% was used as criteria to consider a gene differentially regulated.Authors chose this particular FDR because it was the lowest FDR that did not significantly reduce the number of estimated true positives. WBPaper00044091:Bpseudomallei_repressed_12h
  Transcripts that showed significantly increased expression in animals exposed to 2.5mM ketamine since L1 larva stage. DESeq2 (1.20.0), fold change > 2, p-value < 0.05. WBPaper00064788:ketamine_upregulated
  Coexpression clique No. 282, srj-21-srh-32, on the genome-wide coexpression clique map for the nematode GPL200 platform. All available microarray datasets for the GPL200 platform (Affymetrix C. elegans Genome Array) were obtained from the GEO repository. This included 2243 individual microarray experiments. These were normalized against each other with the software RMAexpress (Bolstad, 2014). Based on these normalized values, Pearsons correlation coefficients were obtained for each probe-probe pair of the 22,620 probes represented on this array type. The resulting list of correlation coefficients was then ranked to generate the ranked coexpression database with information on each probe represented on the GPL200 platform. WBPaper00061527:srj-21-srh-32
  Genome-wide analysis of developmental and sex-regulated gene expression profile. self-organizing map cgc4489_group_7
  Transcripts that showed significantly increased expression in bet-1(uth41) animals comparing to in N2. DESeq2, p-value < 0.05 and fold change > 2. WBPaper00064735:bet-1(uth41)_vs_N2_upregulated
  Transcripts of noncoding genes that showed significantly decreased expression in muscle. DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed. WBPaper00062325:muscle_depleted_noncoding-RNA
  Transcripts that showed more than 4 fold of expression in CB4856 comparing to in N2 animals. DESeq2, fold change > 4. WBPaper00053909:N2_vs_CB4856_downregulated
  Transcripts that showed significantly increased expression after 24 hours of treatment by 50 uM atracurium. Differential expression was assessed using an empirical Bayes moderated t test within limma's linear model framework including the precision weights estimated by voom. Resulting p-values were corrected for multiple testing using the Benjamini-Hochberg false discovery rate. Fold change > 2, p-value < 0.05. WBPaper00061636:atracurium_upregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00044022 10374851 10376884 1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
2034

1 Sequence Ontology Term