WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0061660 Atg12 ligase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0061660 Atg12 ligase activity Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.
GO:0016755 aminoacyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).
GO:0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
GO:0061659 ubiquitin-like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0019777 Atg12 transferase activity Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.
GO:0016746 acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0061660 GO:0000045
has part GO:0061660 GO:0000423
has part GO:0061660 GO:0000425
has part GO:0061660 GO:0016236
has part GO:0061660 GO:0034517
has part GO:0061660 GO:0034727
has part GO:0061660 GO:0035973
has part GO:0061660 GO:0044804
has part GO:0061660 GO:0048102
is_a GO:0019777 GO:0061660
is_a GO:0061659 GO:0061660
is_a GO:0019787 GO:0061660
is_a GO:0016740 GO:0061660
is_a GO:0003824 GO:0061660
is_a GO:0140096 GO:0061660
is_a GO:0016746 GO:0061660
is_a GO:0016755 GO:0061660
is_a GO:0003674 GO:0061660
has part GO:0061660 GO:0061709
has part GO:0061660 GO:0061723
has part GO:0061660 GO:0061724
has part GO:0061660 GO:0061734
has part GO:0061660 GO:0061816
has part GO:0061660 GO:0062093
has part GO:0061660 GO:0098792
has part GO:0061660 GO:0180045

1 Synonyms

Name Type
E3 synonym