WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0019778 Atg12 activating enzyme activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

14 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0019778 Atg12 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0016874 ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.
GO:0016877 ligase activity, forming carbon-sulfur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0016887 ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140657 ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0008641 ubiquitin-like modifier activating enzyme activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.

32 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0019778 GO:0000045
has part GO:0019778 GO:0000423
has part GO:0019778 GO:0000425
has part GO:0019778 GO:0016236
is_a GO:0008641 GO:0019778
is_a GO:0140657 GO:0019778
has part GO:0003674 GO:0019778
is_a GO:0003674 GO:0019778
has part GO:0016462 GO:0019778
has part GO:0017111 GO:0019778
has part GO:0003824 GO:0019778
has part GO:0016787 GO:0019778
has part GO:0016887 GO:0019778
is_a GO:0016877 GO:0019778
is_a GO:0016874 GO:0019778
is_a GO:0003824 GO:0019778
has part GO:0016817 GO:0019778
is_a GO:0140096 GO:0019778
has part GO:0016818 GO:0019778
has part GO:0019778 GO:0034517
has part GO:0019778 GO:0034727
has part GO:0019778 GO:0035973
has part GO:0019778 GO:0044804
has part GO:0019778 GO:0048102
has part GO:0019778 GO:0061709
has part GO:0019778 GO:0061723
has part GO:0019778 GO:0061724
has part GO:0019778 GO:0061734
has part GO:0019778 GO:0061816
has part GO:0019778 GO:0062093

1 Synonyms

Name Type
APG12 activating enzyme activity synonym