WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0000127 transcription factor TFIIIC complex GO

Namespace  cellular_component Obsolete  false
Description  A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

15 Ontology Annotations

Annotation Extension Qualifier
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5 Parents

Identifier Name Description
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005667 transcription regulator complex A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
GO:0090576 RNA polymerase III transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.
GO:0000127 transcription factor TFIIIC complex A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0090576 GO:0000127
is_a GO:0032991 GO:0000127
is_a GO:0005575 GO:0000127
is_a GO:0005667 GO:0000127
part of GO:0000127 GO:0034734
part of GO:0000127 GO:0034735

0 Synonyms