WormMine: GOTerm GO:0000172 ribonuclease MRP complex GO

• Namespace: cellular_component
• Obsolete: false
• Description: A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

32 Ontology Annotations

9 Parents

Identifier	Name	Description
GO:1902494	catalytic complex	A protein complex which is capable of catalytic activity.
GO:0032991	protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575	cellular_component	A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0140535	intracellular protein-containing complex	A protein-containing complex located intracellularly.
GO:1902555	endoribonuclease complex	A protein complex which is capable of endoribonuclease activity.
GO:0000172	ribonuclease MRP complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
GO:0005732	sno(s)RNA-containing ribonucleoprotein complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.
GO:1905348	endonuclease complex	A protein complex which is capable of endonuclease activity.
GO:1990904	ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.

8 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:1902555	GO:0000172
is_a	GO:0005732	GO:0000172
is_a	GO:0140535	GO:0000172
is_a	GO:1902494	GO:0000172
is_a	GO:0032991	GO:0000172
is_a	GO:1905348	GO:0000172
is_a	GO:1990904	GO:0000172
is_a	GO:0005575	GO:0000172

2 Synonyms

• Name: ribonuclease mitochondrial RNA processing complex
• Type: synonym

• Name: RNase MRP complex
• Type: synonym