WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0000178 exosome (RNase complex) GO

Namespace  cellular_component Obsolete  false
Description  A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

51 Ontology Annotations

Annotation Extension Qualifier
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of
  part_of

7 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0000178 exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:1905354 exoribonuclease complex A protein complex which is capable of exoribonuclease activity.

15 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0000178 GO:0000176
is_a GO:0000178 GO:0000176
is_a GO:0000178 GO:0000177
is_a GO:0000178 GO:0000177
part of GO:0005622 GO:0000178
is_a GO:1905354 GO:0000178
part of GO:0005575 GO:0000178
is_a GO:0032991 GO:0000178
is_a GO:0005575 GO:0000178
is_a GO:1902494 GO:0000178
part of GO:0110165 GO:0000178
is_a GO:0000178 GO:0101019
is_a GO:0000178 GO:0101019
is_a GO:0000178 GO:1990061
has part GO:0000178 GO:1990251

2 Synonyms

Name Type
exosome (ribonucleasease complex) synonym
exosome multienzyme ribonuclease complex synonym