WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0010629 negative regulation of gene expression GO

Namespace  biological_process Obsolete  false
Description  Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

88 Ontology Annotations

Annotation Extension Qualifier
has_input(WB:WBGene00002025)|has_input(WB:WBGene00015574) involved_in
has_input(WB:WBGene00001595) involved_in
has_input(WB:WBGene00006873),occurs_in(WBbt:0005409) involved_in
  involved_in
has_input(WB:WBGene00002025),happens_during(GO:0033554)|has_input(WB:WBGene00002025),has_input(ChEBI:22651) involved_in
has_input(WB:WBGene00002025),happens_during(GO:0033554) involved_in
has_input(WB:WBGene00000552) involved_in
has_input(WB:WBGene00002988),results_in_specification_of(WBbt:0003903),part_of(GO:0003388) involved_in
has_input(WB:WBGene00003096) involved_in
has_input(WB:WBGene00002090),happens_during(GO:0071321) involved_in
  involved_in
  involved_in
  involved_in
  involved_in
has_input(WB:WBGene00002980) involved_in
has_input(WB:WBGene00001438),occurs_in(WBbt:0005175),part_of(GO:0008406) involved_in
has_input(WB:WBGene00015574) involved_in
has_input(WB:WBGene00002068),happens_during(GO:0007127) involved_in
  involved_in
has_input(WB:WBGene00001170),occurs_in(WBbt:0006796) involved_in
  involved_in
  involved_in
  involved_in
has_input(WB:WBGene00003229) involved_in
has_input(WB:WBGene00002090)|has_input(WB:WBGene00000920) involved_in
has_input(WB:WBGene00000903),happens_during(GO:0071321)|has_input(WB:WBGene00002090)|has_input(WB:WBGene00000920) involved_in
happens_during(GO:0042742) involved_in
has_input(WB:WBGene00017123)|has_input(WB:WBGene00000915) involved_in
has_input(WB:WBGene00017123)|has_input(WB:WBGene00000915) involved_in
has_input(WB:WBGene00002992)|has_input(WB:WBGene00003024) involved_in

22 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0009058 biosynthetic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0010556 regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010558 negative regulation of macromolecule biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010605 negative regulation of macromolecule metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010629 negative regulation of gene expression Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).

451 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0010629 GO:0000183
is_a GO:0010629 GO:0000184
is_a GO:0010629 GO:0000288
positively regulates GO:0010629 GO:0000288
regulates GO:0010629 GO:0000288
is_a GO:0010629 GO:0000289
part of GO:0010629 GO:0000289
part of GO:0010629 GO:0000290
is_a GO:0010629 GO:0000290
is_a GO:0010629 GO:0000294
is_a GO:0010629 GO:0000512
part of GO:0010629 GO:0000900
part of GO:0010629 GO:0000901
is_a GO:0010629 GO:0000956
is_a GO:0010629 GO:0000958
is_a GO:0010629 GO:0001818
is_a GO:0010629 GO:0002257
is_a GO:0010629 GO:0002546
is_a GO:0010629 GO:0002549
is_a GO:0010629 GO:0002638
is_a GO:0010629 GO:0002701
is_a GO:0010629 GO:0002719
is_a GO:0010629 GO:0002722
is_a GO:0010629 GO:0002725
is_a GO:0010629 GO:0002728
is_a GO:0010629 GO:0002731
is_a GO:0010629 GO:0002734
is_a GO:0010629 GO:0002737
is_a GO:0010629 GO:0002785
is_a GO:0010629 GO:0002787

1 Synonyms

Name Type
gene silencing synonym