WormMine: GOTerm GO:0000213 tRNA-intron lyase activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

20 Ontology Annotations

14 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004519	endonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004518	nuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0140640	catalytic activity, acting on a nucleic acid	Catalytic activity that acts to modify a nucleic acid.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0140101	catalytic activity, acting on a tRNA	Catalytic activity that acts to modify a tRNA.
GO:0140098	catalytic activity, acting on RNA	Catalytic activity that acts to modify RNA.
GO:0004521	RNA endonuclease activity	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0004540	RNA nuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0004549	tRNA-specific ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
GO:0000213	tRNA-intron lyase activity	Catalysis of the reaction: pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
GO:0016892	RNA endonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.

13 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0004549	GO:0000213
is_a	GO:0016892	GO:0000213
is_a	GO:0004519	GO:0000213
is_a	GO:0140101	GO:0000213
is_a	GO:0004518	GO:0000213
is_a	GO:0140640	GO:0000213
is_a	GO:0004540	GO:0000213
is_a	GO:0140098	GO:0000213
is_a	GO:0004521	GO:0000213
is_a	GO:0003674	GO:0000213
is_a	GO:0016787	GO:0000213
is_a	GO:0016788	GO:0000213
is_a	GO:0003824	GO:0000213

3 Synonyms

• Name: tRNA splicing endonuclease activity
• Type: synonym

• Name: tRNA-intron endonuclease activity
• Type: synonym

• Name: tRNA-intron endoribonuclease activity
• Type: synonym