WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0000250 lanosterol synthase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0031559 oxidosqualene cyclase activity Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
GO:0000250 lanosterol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
GO:0016866 intramolecular transferase activity Catalysis of the transfer of a functional group from one position to another within a single molecule.

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0031559 GO:0000250
is_a GO:0003674 GO:0000250
is_a GO:0016853 GO:0000250
is_a GO:0016866 GO:0000250
is_a GO:0003824 GO:0000250

14 Synonyms

Name Type
(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming) synonym
2,3-epoxysqualene lanosterol cyclase activity synonym
2,3-epoxysqualene--lanosterol cyclase activity synonym
2,3-epoxysqualene-lanosterol cyclase activity synonym
2,3-oxidosqualene sterol cyclase activity synonym
2,3-oxidosqualene-lanosterol cyclase activity synonym
lanosterol 2,3-oxidosqualene cyclase activity synonym
OSC synonym
oxidosqualene--lanosterol cyclase activity synonym
oxidosqualene-lanosterol cyclase activity synonym
oxidosqualene:lanosterol cyclase activity synonym
squalene 2,3-epoxide:lanosterol cyclase activity synonym
squalene epoxidase-cyclase activity synonym
squalene-2,3-oxide-lanosterol cyclase activity synonym