WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0000257 nitrilase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

6 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GO:0016815 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.
GO:0000257 nitrilase activity Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.

11 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016815 GO:0000257
is_a GO:0016787 GO:0000257
is_a GO:0003674 GO:0000257
is_a GO:0016810 GO:0000257
is_a GO:0003824 GO:0000257
is_a GO:0000257 GO:0018761
is_a GO:0000257 GO:0018762
is_a GO:0000257 GO:0047426
is_a GO:0000257 GO:0047427
is_a GO:0000257 GO:0047428
is_a GO:0000257 GO:0080061

3 Synonyms

Name Type
acetonitrilase activity synonym
benzonitrilase activity synonym
nitrile aminohydrolase activity synonym