28 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0009987 | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0008150 | biological_process | A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
| GO:0003674 | molecular_function | A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
| GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
| GO:0006281 | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| GO:0051716 | cellular response to stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
| GO:0044238 | primary metabolic process | The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
| GO:0050896 | response to stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
| GO:0090304 | nucleic acid metabolic process | Any cellular metabolic process involving nucleic acids. |
| GO:0006950 | response to stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). |
| GO:0033554 | cellular response to stress | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). |
| GO:0006139 | nucleobase-containing compound metabolic process | Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
| GO:0006974 | DNA damage response | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. |
| GO:0006259 | DNA metabolic process | Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. |
| GO:0008152 | metabolic process | A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. |
| GO:0043170 | macromolecule metabolic process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
| GO:0004520 | DNA endonuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. |
| GO:0004519 | endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| GO:0004536 | DNA nuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. |
| GO:0004518 | nuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids. |
| GO:0140640 | catalytic activity, acting on a nucleic acid | Catalytic activity that acts to modify a nucleic acid. |
| GO:0140097 | catalytic activity, acting on DNA | Catalytic activity that acts to modify DNA. |
| GO:0016787 | hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| GO:0016788 | hydrolase activity, acting on ester bonds | Catalysis of the hydrolysis of any ester bond. |
| GO:0006302 | double-strand break repair | The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. |
| GO:0000735 | removal of nonhomologous ends | The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. |
| GO:0045002 | double-strand break repair via single-strand annealing | Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats. |
| GO:0000736 | double-strand break repair via single-strand annealing, removal of nonhomologous ends | During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. |
39 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0045002 | GO:0000736 |
| is_a | GO:0000735 | GO:0000736 |
| part of | GO:0045002 | GO:0000736 |
| is_a | GO:0000735 | GO:0000736 |
| part of | GO:0008152 | GO:0000736 |
| has part | GO:0004518 | GO:0000736 |
| part of | GO:0008150 | GO:0000736 |
| has part | GO:0004519 | GO:0000736 |
| part of | GO:0090304 | GO:0000736 |
| has part | GO:0004536 | GO:0000736 |
| has part | GO:0003824 | GO:0000736 |
| part of | GO:0033554 | GO:0000736 |
| is_a | GO:0006259 | GO:0000736 |
| is_a | GO:0044238 | GO:0000736 |
| has part | GO:0016787 | GO:0000736 |
| is_a | GO:0006139 | GO:0000736 |
| is_a | GO:0009987 | GO:0000736 |
| is_a | GO:0090304 | GO:0000736 |
| part of | GO:0043170 | GO:0000736 |
| part of | GO:0050896 | GO:0000736 |
| is_a | GO:0008150 | GO:0000736 |
| part of | GO:0006302 | GO:0000736 |
| is_a | GO:0008152 | GO:0000736 |
| has part | GO:0004520 | GO:0000736 |
| has part | GO:0003674 | GO:0000736 |
| part of | GO:0006281 | GO:0000736 |
| is_a | GO:0043170 | GO:0000736 |
| part of | GO:0044238 | GO:0000736 |
| has part | GO:0140640 | GO:0000736 |
| has part | GO:0140097 | GO:0000736 |
