WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0001771 immunological synapse formation GO

Namespace  biological_process Obsolete  false
Description  The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001775 cell activation A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0009988 cell-cell recognition Cell recognition between cells. May involve the formation of specialized cell junctions.
GO:0001771 immunological synapse formation The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
GO:0008037 cell recognition The process in which a cell in an organism interprets its surroundings.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0009988 GO:0001771
part of GO:0046649 GO:0001771
part of GO:0032501 GO:0001771
part of GO:0002376 GO:0001771
is_a GO:0008037 GO:0001771
part of GO:0045321 GO:0001771
is_a GO:0009987 GO:0001771
is_a GO:0008150 GO:0001771
part of GO:0008150 GO:0001771
part of GO:0009987 GO:0001771
part of GO:0001775 GO:0001771
regulates GO:0001771 GO:2000520
regulates GO:0001771 GO:2000520
negatively regulates GO:0001771 GO:2000521
negatively regulates GO:0001771 GO:2000521
regulates GO:0001771 GO:2000521
positively regulates GO:0001771 GO:2000522
positively regulates GO:0001771 GO:2000522
regulates GO:0001771 GO:2000522
part of GO:0001771 GO:2000526
part of GO:0001771 GO:2000526

1 Synonyms

Name Type
formation of immunological synapse synonym