WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO

Namespace  biological_process Obsolete  false
Description  An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002250 adaptive immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.

303 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0002460 GO:0001788
is_a GO:0002460 GO:0001794
is_a GO:0002460 GO:0001795
regulates GO:0002460 GO:0001796
regulates GO:0002460 GO:0001797
negatively regulates GO:0002460 GO:0001797
regulates GO:0002460 GO:0001798
positively regulates GO:0002460 GO:0001798
regulates GO:0002460 GO:0001799
negatively regulates GO:0002460 GO:0001800
regulates GO:0002460 GO:0001800
regulates GO:0002460 GO:0001801
positively regulates GO:0002460 GO:0001801
is_a GO:0002460 GO:0001802
regulates GO:0002460 GO:0001803
negatively regulates GO:0002460 GO:0001804
regulates GO:0002460 GO:0001804
regulates GO:0002460 GO:0001805
positively regulates GO:0002460 GO:0001805
is_a GO:0002460 GO:0001806
regulates GO:0002460 GO:0001807
negatively regulates GO:0002460 GO:0001808
regulates GO:0002460 GO:0001808
regulates GO:0002460 GO:0001809
positively regulates GO:0002460 GO:0001809
regulates GO:0002460 GO:0001810
regulates GO:0002460 GO:0001811
negatively regulates GO:0002460 GO:0001811
regulates GO:0002460 GO:0001812
positively regulates GO:0002460 GO:0001812

0 Synonyms