WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0002140 stereocilia tip link GO

Namespace  cellular_component Obsolete  false
Description  A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0002139 stereocilia coupling link A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.
GO:0032421 stereocilium bundle A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.
GO:0098862 cluster of actin-based cell projections A cell part consisting of multiple, closely packed actin-based cell projections.
GO:0002140 stereocilia tip link A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0002139 GO:0002140
part of GO:0098862 GO:0002140
part of GO:0110165 GO:0002140
part of GO:0005575 GO:0002140
part of GO:0032421 GO:0002140
is_a GO:0110165 GO:0002140
is_a GO:0005575 GO:0002140
part of GO:0002140 GO:1990427
part of GO:0002140 GO:1990434
part of GO:0002140 GO:1990435

0 Synonyms