WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0002341 central B cell anergy GO

Namespace  biological_process Obsolete  false
Description  Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

30 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0007275 multicellular organism development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0048856 anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048731 system development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0048468 cell development The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.
GO:0048869 cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0030154 cell differentiation The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001775 cell activation A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0042113 B cell activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0030098 lymphocyte differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0030097 hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
GO:0002521 leukocyte differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:1903131 mononuclear cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.
GO:0030183 B cell differentiation The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
GO:0002520 immune system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0002339 B cell selection The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
GO:0002507 tolerance induction A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
GO:0002249 lymphocyte anergy Any process contributing to lymphocyte anergy, a state of functional inactivation.
GO:0002340 central B cell selection Any B cell selection process that occurs in the bone marrow.
GO:0002510 central B cell tolerance induction Tolerance induction of B cells in the bone marrow.
GO:0002341 central B cell anergy Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.
GO:0002515 B cell anergy Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
GO:0002514 B cell tolerance induction A process involving any mechanism for tolerance induction in B cells.
GO:0002508 central tolerance induction Tolerance induction in the central lymphoid organs: the thymus and bone marrow.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0002510 GO:0002341
is_a GO:0002515 GO:0002341
part of GO:0002340 GO:0002341
part of GO:0002521 GO:0002341
is_a GO:0008150 GO:0002341
part of GO:0002520 GO:0002341
part of GO:0030154 GO:0002341
part of GO:0048468 GO:0002341
part of GO:0007275 GO:0002341
is_a GO:0002507 GO:0002341
part of GO:0008150 GO:0002341
is_a GO:0002249 GO:0002341
part of GO:0042113 GO:0002341
part of GO:0002339 GO:0002341
part of GO:0030183 GO:0002341
part of GO:0048856 GO:0002341
part of GO:0009987 GO:0002341
part of GO:0002514 GO:0002341
part of GO:0002376 GO:0002341
part of GO:0032502 GO:0002341
part of GO:0032501 GO:0002341
part of GO:0048731 GO:0002341
is_a GO:0002514 GO:0002341
part of GO:0045321 GO:0002341
part of GO:1903131 GO:0002341
part of GO:0046649 GO:0002341
is_a GO:0002376 GO:0002341
part of GO:0002508 GO:0002341
part of GO:0030097 GO:0002341
part of GO:0030098 GO:0002341

3 Synonyms

Name Type
central B lymphocyte anergy synonym
central B-cell anergy synonym
central B-lymphocyte anergy synonym