WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0042267 natural killer cell mediated cytotoxicity GO

Namespace  biological_process Obsolete  false
Description  The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

22 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
GO:0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0043207 response to external biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
GO:0044419 biological process involved in interspecies interaction between organisms Any process evolved to enable an interaction with an organism of a different species.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001909 leukocyte mediated cytotoxicity The directed killing of a target cell by a leukocyte.
GO:0002449 lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002252 immune effector process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.
GO:0001906 cell killing Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0045087 innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0140546 defense response to symbiont Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.
GO:0098542 defense response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
GO:0002228 natural killer cell mediated immunity The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
GO:0042267 natural killer cell mediated cytotoxicity The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

45 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042267 GO:0002420
regulates GO:0042267 GO:0002858
negatively regulates GO:0042267 GO:0002859
regulates GO:0042267 GO:0002859
positively regulates GO:0042267 GO:0002860
regulates GO:0042267 GO:0002860
is_a GO:0002228 GO:0042267
is_a GO:0001909 GO:0042267
is_a GO:0002376 GO:0042267
is_a GO:0009607 GO:0042267
is_a GO:0006952 GO:0042267
is_a GO:0002443 GO:0042267
is_a GO:0045087 GO:0042267
is_a GO:0140546 GO:0042267
is_a GO:0009987 GO:0042267
is_a GO:0098542 GO:0042267
is_a GO:0009605 GO:0042267
is_a GO:0006955 GO:0042267
is_a GO:0002449 GO:0042267
is_a GO:0050896 GO:0042267
is_a GO:0001906 GO:0042267
is_a GO:0008150 GO:0042267
is_a GO:0043207 GO:0042267
is_a GO:0051707 GO:0042267
is_a GO:0044419 GO:0042267
is_a GO:0006950 GO:0042267
is_a GO:0002252 GO:0042267
regulates GO:0042267 GO:0042269
regulates GO:0042267 GO:0042269
negatively regulates GO:0042267 GO:0042270

9 Synonyms

Name Type
killer activity synonym
natural killer cell mediated cytolysis synonym
natural killer-cell mediated cytolysis synonym
natural killer cell mediated cell death synonym
natural killer cell mediated cell killing synonym
NK cell mediated cytolysis synonym
NK cell mediated cytotoxicity synonym
NK cell mediated cell death synonym
NK cell mediated cell killing synonym