16 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:1902494 | catalytic complex | A protein complex which is capable of catalytic activity. |
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0140513 | nuclear protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. |
| GO:0090575 | RNA polymerase II transcription regulator complex | A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II. |
| GO:0005667 | transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
| GO:0000123 | histone acetyltransferase complex | A protein complex that possesses histone acetyltransferase activity. |
| GO:0031248 | protein acetyltransferase complex | A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule. |
| GO:1990234 | transferase complex | A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). |
| GO:1902493 | acetyltransferase complex | A protein complex which is capable of acetyltransferase activity. |
| GO:0140535 | intracellular protein-containing complex | A protein-containing complex located intracellularly. |
| GO:0070461 | SAGA-type complex | A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs). |
| GO:0016592 | mediator complex | A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. |
| GO:0002929 | MECO complex | A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II. |
| GO:0140672 | ATAC complex | A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation. |
| GO:0070847 | core mediator complex | A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. |
17 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| has part | GO:0016592 | GO:0002929 |
| has part | GO:0140672 | GO:0002929 |
| is_a | GO:0032991 | GO:0002929 |
| has part | GO:0005667 | GO:0002929 |
| is_a | GO:0005575 | GO:0002929 |
| has part | GO:0005575 | GO:0002929 |
| has part | GO:1990234 | GO:0002929 |
| has part | GO:0000123 | GO:0002929 |
| has part | GO:0031248 | GO:0002929 |
| has part | GO:0032991 | GO:0002929 |
| has part | GO:0070461 | GO:0002929 |
| has part | GO:0090575 | GO:0002929 |
| has part | GO:0070847 | GO:0002929 |
| has part | GO:1902494 | GO:0002929 |
| has part | GO:1902493 | GO:0002929 |
| has part | GO:0140513 | GO:0002929 |
| has part | GO:0140535 | GO:0002929 |
