WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0098531 ligand-modulated transcription factor activity GO

Namespace  molecular_function Obsolete  false
Description  A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific genes and gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

26 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0019219 regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003676 nucleic acid binding Binding to a nucleic acid.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:2001141 regulation of RNA biosynthetic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
GO:0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0010556 regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0006355 regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:1990837 sequence-specific double-stranded DNA binding Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003690 double-stranded DNA binding Binding to double-stranded DNA.
GO:0043565 sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
GO:0001067 transcription regulatory region nucleic acid binding Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
GO:0000976 transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
GO:0140110 transcription regulator activity A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.
GO:0003700 DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
GO:0098531 ligand-modulated transcription factor activity A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific genes and gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.

36 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098531 GO:0003707
is_a GO:0098531 GO:0004879
is_a GO:0098531 GO:0004883
is_a GO:0098531 GO:0030284
is_a GO:0098531 GO:0031963
has part GO:0098531 GO:0038185
is_a GO:0098531 GO:0038186
is_a GO:0003700 GO:0098531
part of GO:0006355 GO:0098531
part of GO:0009889 GO:0098531
has part GO:0043565 GO:0098531
has part GO:0000976 GO:0098531
part of GO:0010556 GO:0098531
part of GO:2001141 GO:0098531
part of GO:0050794 GO:0098531
has part GO:0003690 GO:0098531
part of GO:0060255 GO:0098531
has part GO:0003676 GO:0098531
has part GO:0003677 GO:0098531
has part GO:0003674 GO:0098531
part of GO:0065007 GO:0098531
has part GO:1990837 GO:0098531
part of GO:0051252 GO:0098531
part of GO:0010468 GO:0098531
is_a GO:0003674 GO:0098531
part of GO:0080090 GO:0098531
part of GO:0019222 GO:0098531
has part GO:0005488 GO:0098531
is_a GO:0140110 GO:0098531
part of GO:0050789 GO:0098531

3 Synonyms

Name Type
ligand-activated transcription factor activity synonym
direct ligand regulated sequence-specific DNA binding transcription factor activity synonym
transcription factor activity, direct ligand regulated sequence-specific DNA binding synonym