WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0016840 carbon-nitrogen lyase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

4 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0016840 carbon-nitrogen lyase activity Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).

42 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016840 GO:0003839
is_a GO:0016840 GO:0003941
is_a GO:0016840 GO:0004018
is_a GO:0016840 GO:0004056
is_a GO:0016840 GO:0004397
is_a GO:0016840 GO:0004598
is_a GO:0016840 GO:0004794
is_a GO:0016840 GO:0008473
is_a GO:0016840 GO:0008721
is_a GO:0016840 GO:0008797
is_a GO:0016840 GO:0008824
is_a GO:0016840 GO:0008838
is_a GO:0016840 GO:0008851
is_a GO:0016829 GO:0016840
is_a GO:0003674 GO:0016840
is_a GO:0003824 GO:0016840
is_a GO:0016840 GO:0016841
is_a GO:0016840 GO:0016842
is_a GO:0016840 GO:0016843
is_a GO:0016840 GO:0030412
is_a GO:0016840 GO:0030848
is_a GO:0016840 GO:0036381
is_a GO:0016840 GO:0044689
is_a GO:0016840 GO:0045548
is_a GO:0016840 GO:0047447
is_a GO:0016840 GO:0047459
is_a GO:0016840 GO:0047566
is_a GO:0016840 GO:0047698
is_a GO:0016840 GO:0047766
is_a GO:0016840 GO:0047930

1 Synonyms

Name Type
other carbon-nitrogen lyase activity synonym