WormMine: GOTerm GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

15 Ontology Annotations

10 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0160215	deacylase activity	Catalysis of the reaction: R-CO-X + H2O = R-COOH + HX, hydrolysis of an acyl group or groups from a substrate molecule.
GO:0141126	short-chain fatty acyl-CoA hydrolase activity	Catalysis of the reaction: a short-chain fatty acyl-CoA + H2O = a short fatty acid + CoA + H+. A short-chain fatty acid has an aliphatic tail of less than 6 carbons.
GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity	Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
GO:0047617	fatty acyl-CoA hydrolase activity	Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.
GO:0016289	acyl-CoA hydrolase activity	Catalysis of the reaction: an acyl-CoA + H2O = a carboxylate + CoA + H+.
GO:0016790	thiolester hydrolase activity	Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.

9 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0141126	GO:0003860
is_a	GO:0047617	GO:0003860
is_a	GO:0016289	GO:0003860
is_a	GO:0003674	GO:0003860
is_a	GO:0160215	GO:0003860
is_a	GO:0016787	GO:0003860
is_a	GO:0016788	GO:0003860
is_a	GO:0003824	GO:0003860
is_a	GO:0016790	GO:0003860

3 Synonyms

• Name: 3-hydroxy-isobutyryl CoA hydrolase activity
• Type: synonym

• Name: 3-hydroxy-2-methylpropanoyl-CoA hydrolase activity
• Type: synonym

• Name: HIB CoA deacylase activity
• Type: synonym