WormMine: GOTerm GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

45 Ontology Annotations

12 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0140640	catalytic activity, acting on a nucleic acid	Catalytic activity that acts to modify a nucleic acid.
GO:0140097	catalytic activity, acting on DNA	Catalytic activity that acts to modify DNA.
GO:0005488	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003676	nucleic acid binding	Binding to a nucleic acid.
GO:0016853	isomerase activity	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0120543	macromolecular conformation isomerase activity	Catalysis of a reaction that alters the macromolecular conformation of a molecule.
GO:0003677	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0120545	nucleic acid conformation isomerase activity	Catalysis of a reaction that alters the conformation of a nucleic acid.
GO:0003916	DNA topoisomerase activity	Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

12 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0003916	GO:0003917
is_a	GO:0003674	GO:0003917
is_a	GO:0016853	GO:0003917
is_a	GO:0120545	GO:0003917
has part	GO:0003674	GO:0003917
is_a	GO:0003824	GO:0003917
has part	GO:0003677	GO:0003917
has part	GO:0003676	GO:0003917
is_a	GO:0120543	GO:0003917
has part	GO:0005488	GO:0003917
is_a	GO:0140640	GO:0003917
is_a	GO:0140097	GO:0003917

10 Synonyms

• Name: untwisting enzyme activity
• Type: synonym

• Name: deoxyribonucleate topoisomerase
• Type: synonym

• Name: nicking-closing enzyme activity
• Type: synonym

• Name: DNA topoisomerase I activity
• Type: synonym

• Name: relaxing enzyme activity
• Type: synonym

• Name: omega-protein activity
• Type: synonym

• Name: topoisomerase
• Type: synonym

• Name: swivelase activity
• Type: synonym

• Name: type I topoisomerase activity
• Type: synonym

• Name: type I DNA topoisomerase activity
• Type: synonym