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WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0003925 G protein activity GO
Namespace  molecular_function Obsolete  false
Description  A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).
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0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

5 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables

12 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
GO:0003925 G protein activity A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).

12 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0003924 GO:0003925
is_a GO:0098772 GO:0003925
has part GO:0005515 GO:0003925
is_a GO:0016817 GO:0003925
is_a GO:0016818 GO:0003925
is_a GO:0003824 GO:0003925
has part GO:0003674 GO:0003925
is_a GO:0016462 GO:0003925
has part GO:0005488 GO:0003925
is_a GO:0017111 GO:0003925
is_a GO:0016787 GO:0003925
is_a GO:0003674 GO:0003925

11 Synonyms

Name Type
heterotrimeric G-protein GTPase activity synonym
small monomeric GTPase activity synonym
large G-protein activity synonym
large G-protein GTPase activity synonym
Ras superfamily protein synonym
signaling G protein activity synonym
small G-protein synonym
small GTPase synonym
small GTPase activity synonym
small monomeric G protein activity synonym
GO:0003927 alt_id