WormMine: GOTerm GO:0004090 carbonyl reductase (NADPH) activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

7 Ontology Annotations

9 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491	oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+.
GO:0008106	alcohol dehydrogenase (NADP+) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or ketone + NADPH + H+.
GO:0004033	aldo-keto reductase (NADPH) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.
GO:0004090	carbonyl reductase (NADPH) activity	Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.

8 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0008106	GO:0004090
is_a	GO:0004033	GO:0004090
is_a	GO:0003674	GO:0004090
is_a	GO:0018455	GO:0004090
is_a	GO:0016614	GO:0004090
is_a	GO:0016491	GO:0004090
is_a	GO:0003824	GO:0004090
is_a	GO:0016616	GO:0004090

10 Synonyms

• Name: NADPH-dependent carbonyl reductase activity
• Type: synonym

• Name: carbonyl reductase activity
• Type: synonym

• Name: nonspecific NADPH-dependent carbonyl reductase activity
• Type: synonym

• Name: NADPH2-dependent carbonyl reductase activity
• Type: synonym

• Name: secondary-alcohol:NADP+ oxidoreductase activity
• Type: synonym

• Name: prostaglandin 9-ketoreductase activity
• Type: synonym

• Name: xenobiotic ketone reductase activity
• Type: synonym

• Name: aldehyde reductase 1
• Type: synonym

• Name: ALR3
• Type: synonym

• Name: aldehyde reductase I activity
• Type: synonym