WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0017171 serine hydrolase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

4 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0017171 serine hydrolase activity Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0017171 GO:0004185
is_a GO:0017171 GO:0004252
negatively regulates GO:0017171 GO:0004867
is_a GO:0017171 GO:0008236
is_a GO:0017171 GO:0008240
is_a GO:0017171 GO:0009002
is_a GO:0016787 GO:0017171
is_a GO:0003824 GO:0017171
is_a GO:0003674 GO:0017171
is_a GO:0017171 GO:0070008
is_a GO:0017171 GO:0070009
is_a GO:0017171 GO:0071972
regulates GO:0017171 GO:1900003
regulates GO:0017171 GO:1900004
negatively regulates GO:0017171 GO:1900004
regulates GO:0017171 GO:1900005
positively regulates GO:0017171 GO:1900005
negatively regulates GO:0017171 GO:1902572

0 Synonyms