WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

8 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
GO:0016229 steroid dehydrogenase activity Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0033764 GO:0004303
is_a GO:0003674 GO:0004303
is_a GO:0016229 GO:0004303
is_a GO:0016614 GO:0004303
is_a GO:0016616 GO:0004303
is_a GO:0016491 GO:0004303
is_a GO:0003824 GO:0004303

13 Synonyms

Name Type
estrogen 17-oxidoreductase activity synonym
17-beta-HSD activity synonym
17beta-HSD synonym
20alpha-hydroxysteroid dehydrogenase synonym
17-beta-estradiol dehydrogenase activity synonym
17beta,20alpha-hydroxysteroid dehydrogenase activity synonym
17-beta-hydroxysteroid dehydrogenase activity synonym
17beta-hydroxysteroid dehydrogenase activity synonym
17beta-estradiol dehydrogenase activity synonym
estradiol 17beta-dehydrogenase activity synonym
estradiol 17-beta-dehydrogenase activity synonym
estradiol-17beta:NAD(P)+ 17-oxidoreductase activity synonym
estradiol dehydrogenase activity synonym