WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004326 tetrahydrofolylpolyglutamate synthase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

15 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables

18 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0009058 biosynthetic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0016874 ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.
GO:0006575 modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016881 acid-amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0004326 tetrahydrofolylpolyglutamate synthase activity Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
GO:0042398 modified amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0046900 tetrahydrofolylpolyglutamate metabolic process The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
GO:0009396 folic acid-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
GO:0042558 pteridine-containing compound metabolic process The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0042559 pteridine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0006760 folic acid-containing compound metabolic process The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016881 GO:0004326
part of GO:0046901 GO:0004326
part of GO:0009987 GO:0004326
is_a GO:0016874 GO:0004326
is_a GO:0003824 GO:0004326
part of GO:0042398 GO:0004326
part of GO:0046900 GO:0004326
is_a GO:0003674 GO:0004326
part of GO:0008150 GO:0004326
part of GO:0009396 GO:0004326
part of GO:0008152 GO:0004326
part of GO:0042558 GO:0004326
part of GO:0042559 GO:0004326
part of GO:0006760 GO:0004326
part of GO:0009058 GO:0004326
is_a GO:0016879 GO:0004326
part of GO:0006575 GO:0004326

15 Synonyms

Name Type
N10-formyltetrahydropteroyldiglutamate synthetase activity synonym
N(10)-formyltetrahydropteroyldiglutamate synthetase activity synonym
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity synonym
tetrahydrofolate synthase activity synonym
tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming) synonym
tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming) synonym
folate polyglutamate synthetase activity synonym
folylpoly-gamma-glutamate synthase activity synonym
folylpoly(gamma-glutamate) synthase activity synonym
folylpolyglutamate synthase activity synonym
folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity synonym
folylpolyglutamyl synthetase activity synonym
folylpolyglutamate synthetase activity synonym
FPGS activity synonym
formyltetrahydropteroyldiglutamate synthetase activity synonym