WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004355 glutamate synthase (NADPH) activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0015930 glutamate synthase activity Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.
GO:0004355 glutamate synthase (NADPH) activity Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0015930 GO:0004355
is_a GO:0003674 GO:0004355
is_a GO:0016491 GO:0004355
is_a GO:0003824 GO:0004355
is_a GO:0016638 GO:0004355

13 Synonyms

Name Type
GOGAT activity synonym
L-glutamate synthase activity synonym
L-glutamate synthetase activity synonym
glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity synonym
glutamate synthetase (NADP) activity synonym
glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity synonym
glutamine-ketoglutaric aminotransferase activity synonym
L-glutamate:NADP+ oxidoreductase (transaminating) synonym
L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity synonym
NADPH GOGAT synonym
NADPH-dependent glutamate synthase activity synonym
NADPH-glutamate synthase activity synonym
NADPH-linked glutamate synthase synonym